EMG measurements of respiratory muscles for the titration of nocturnal non-invasive ventilation in stable chronic obstructive pulmonary disease patients; a randomised cross-over trial.

EMG measurements of respiratory muscles for the titration of nocturnal non-invasive ventilation in stable chronic obstructive pulmonary disease patients; a randomised cross-over trial. - Respiratory EMG for NIV titration in stable COPD.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON42530

Enrollment

Registered

2015-11-02

Start date

2015-11-19

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD longemfyseem

Interventions

Intervention: One group will be initiated on NIV according to standard care protocol. For the other group, additional EMG measures whilst on NIV will be made to titrate NIV.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Chronic Obstructive Pulmonary Diseases GOLD stage III or IV (FEV1 6.0 kPa at rest during daytime, in stable condition - Stable COPD (pH 18 years

Exclusion criteria

Exclusion criteria: - Respiratory failure of any other cause, for example concomitant neuromuscular disease. - Already initiated chronic NIV

Design outcomes

Primary

Measure	Time frame
Our primary outcome is nocturnal gas exchange after 6 weeks NIV.	—

Secondary

Measure	Time frame
Secondary outcomes will be better patient comfort, health-realted quality of life, lung function, and compliance with the ventilator after 6 weeks. Furthermore, patient-ventilator asynchrony will be assessed.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)