Visual Function in Albinism: contribution of ocular abnormalities and pigmentation.

Visual Function in Albinism: contribution of ocular abnormalities and pigmentation. - ViFA

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42506

Enrollment

Registered

2015-08-25

Start date

2016-08-05

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Albinism hair and skin Hypopigmentation of the eyes only or the eyes

Interventions

None listed

Eligibility

Age

12 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients diagnosed with albinism, Idiopathic Infantile Nystagmus (IIN) or FHONDA from the LUMC and/or Bartiméus. Patients must be older than 12 years of age.

Exclusion criteria

Exclusion criteria: Patients with another condition besides albinism, FHONDA or IIN that could cause reduced visual function.

Design outcomes

Primary

Measure	Time frame
The presence and severity of opticopathy in patients with albinism with relatively poor BCVA and relatively good BCVA, i.e. less than 0.3 logMar and more than 0.8 logMar, respectively.	—

Secondary

Measure	Time frame
The difference in clinical and electrophysiological profile between patients with albinism with relatively poor and good BCVA. Furthermore, the difference in clinical and electrophysiological profile of patients with albinism, FHONDA and IIN. Clinical profile includes BCVA, refraction, strabismus, stereopsis, amblyopia, nystagmus, photophobia, iris transillumination, and macula and optic nerve characteristics. Electrophysiological profile includes VEP misrouting and VEP opticopathy (pattern VEP) analysis in detail.	—

Measure

Time frame

The difference in clinical and electrophysiological profile between patients with albinism with relatively poor and good BCVA. Furthermore, the difference in clinical and electrophysiological profile of patients with albinism, FHONDA and IIN. Clinical profile includes BCVA, refraction, strabismus, stereopsis, amblyopia, nystagmus, photophobia, iris transillumination, and macula and optic nerve characteristics. Electrophysiological profile includes VEP misrouting and VEP opticopathy (pattern VEP) analysis in detail.

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Countries

Netherlands

Outcome results