Cervical cancer
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: * Clinical indication for chemoradiotherapy with curative intent (one of the following): -FIGO [1] stage IA, IB1 or IIA1 cervical cancer with regional lymph node pathology, -FIGO stage IA, IB1 or IIA1 cervical cancer with contraindications for surgery -FIGO stage IB2, IIA2, IIB, IIIA, IIIB, or IVA cervical cancer * Medical condition that allows chemoradiotherapy with curative intent * Age * 18 years * Signed informed consent, obtained before the acquisition of the first additional MRI scan * Able to comply with the variable bladder filling protocol (drinking and voiding instructions, this protocol is part of standard clinical care)
Exclusion criteria
Exclusion criteria: * Patients who meet exclusion criteria for MRI at 1.5T following the protocol of the department of Radiology of the UMC Utrecht * Patients who are mentally or otherwise disabled and/or considered legally incapable * History of previous pelvic radiotherapy * Pregnant or breast-feeding patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We will develop a new workflow for MRI-guided adaptive radiotherapy, assessing the accuracy of semi-automatic delineation of target volume and critical organs. Treatment remains according to standard clinical practice, but we will (digitally) simulate our new workflow using the acquired MRI scans. | — |
Countries
Netherlands
Outcome results
None listed