Dementia
Conditions
Interventions
The interactive cycling training consists of cycling on a home-trainer. During
the cycling participants follow the route on a screen and have to conduct
simple cognitive tasks. Participants will tra
Sponsors
Geriatrie
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Diagnosis of dementia Mini Mental State Examination (Folstein and Folstein 1975) score > 20 Clinical Dementia Rating (CDR) score 0.5 -1.0, and still capable to give informed consent Having insufficient physical activity according to the ACSM guideline for older adults (maximum of 30 minutes five days a week moderate intensity)
Exclusion criteria
Exclusion criteria: Wheelchair bound Use of specifically dementia targeted nutritional supplements (e.g. Souvenaid) within the last 3 months Cardiovascular problems that limit physical activity Serious neurological or orthopedic disorder that limit physical activity Diagnosis of severe depression, bipolar disorder or psychotic disorder (DSM-IV) Current alcohol or drug abuse (DSM-IV) Problems with the Dutch language Severe hearing or visual problems not able to correct with the use of a hearing device/glasses
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Our primary outcome measure is change in executive functioning, before and after the training intervention, in the interactive cycling group. Executive function will be measured with neuropsychological tests. Furthermore verbal and visual-spatial memory will be assessed. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures are physical functioning measured with performance-based tests, Brain Derived Neurothropic Factor (BDNF) measured via blood sample, prefrontal cortex activation measured with functional Near Infrared Spectroscopy (by fNIRS) and changes in activities of daily living (ADL), mood and quality of life, as measured by questionnaires | — |
Countries
Netherlands
Outcome results
None listed