The effect of therapeutic treatments in the transplant model of psoriasis; in which a psoriatic lesion is induced in non-lesional skin transplanted onto immune-deficient (BNX) mice by injecting super-antigen activated peripheral blood cells intra-dermally into the transplant.

The effect of therapeutic treatments in the transplant model of psoriasis; in which a psoriatic lesion is induced in non-lesional skin transplanted onto immune-deficient (BNX) mice by injecting super-antigen activated peripheral blood cells intra-dermally into the transplant. - The effect of therapeutic treatments in the transplant model of psoriasis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42470

Enrollment

Registered

2015-10-26

Start date

2016-01-07

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psoriasis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with psoriasis vulgaris, mild to moderate.

Exclusion criteria

Exclusion criteria: Volunteers should not: - use light therapy or systemic drugs such as methotrexate or cyclosporine A. - use local topical corticosteroids. - develop psoriasis at wound sites (Köbner phenomenon). - have other skin diseases. - be pregnant

Design outcomes

Primary

Measure	Time frame
Transplant epidermal thickness.	—

Secondary

Measure	Time frame
Number of dividing epidermal keratinocytes.	—

Countries

Netherlands

Outcome results