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The Pupil Response and Individual Listening Load (PupILL): Towards the development of a clinically applicable measure of cognitive processing load in daily life hearing

The Pupil Response and Individual Listening Load (PupILL): Towards the development of a clinically applicable measure of cognitive processing load in daily life hearing - PupILL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON42449
Enrollment
84
Registered
2015-12-14
Start date
2016-05-12
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hearing impairment hearing loss

Interventions

None listed

Sponsors

Vrije Universiteit Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Aged between 18 and 80 years of age, native speakers of Dutch, normal or corrected-to-normal eyesight. Participants should have at least 3 cm long hair at the posterior part of the head. Listeners with hearing loss should have average pure tone hearing thresholds (across 1000, 2000 and 4000 Hz) of at least 35 dB HL in both ears.

Exclusion criteria

Exclusion criteria: Listeners with normal hearing should have age-normal hearing (ISO 7029, 2000). General exclusion criteria: epilepsy, dyslexia or other reading problems, having a history of a neurological, psychiatric, endocrine or cardiovascular diseases or using psychoactive drugs, β blockers, or smoking (> 6 cigarettes per day). The exclusion criteria also include (eye-) diseases such as diabetes mellitus and cataract that may influence the pupil dilation response and pupil light reflex.

Design outcomes

Primary

MeasureTime frame
The main study parameters include the pupil dilation response during listening to speech, the saliva cortisol and alpha-amylase level during speech perception tests, the long-term cortisol levels in scalp hair and the pupil light reflex.

Secondary

MeasureTime frame
Degree of hearing loss (normal hearing controls), drug use, screening visual abilities - in order to check inclusion criteria.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)