Q fever fatigue syndrome (QFS) / chronic Q fever
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients meeting the criteria of proven or probable chronic Q-fever according to the Dutch consensus guidelines on chronic Q-fever diagnostics and diagnosed after the Q-fever outbreak of 2007 are eligible for this study.;Patients with QFS are diagnosed according to the following criteria: - Fatigue persisting longer than 6 months - Laboratory-confirmed acute Q-fever - no recent (
Exclusion criteria
Exclusion criteria: Patients diagnosed with a possible chronic Q-fever are not eligible for participation in this study, as the majority of these patients ultimately appear not to have chronic Q-fever.;Patients with diabetes and persons in the reference group from the general population will be excluded if they have had a positive Q-fever diagnosis at any time in their life, including no diagnosis of chronic Q-fever or QFS.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters will be the summary scores on work status and psychosocial functioning, measured with several questionnaires (e.g. the Nijmegen Clinical Screening Instrument, SF-36, Work Ability Index and the Maudsley Marital Questionnaire). | — |
Secondary
| Measure | Time frame |
|---|---|
| Various validated questionnaires will be used to measure possible mediating factors, baseline values and/or confounders, such as: fatgue, cognitive functioning, illness perception, age, gender, education level, health and disease related parameters and co-morbidity. | — |
Countries
Netherlands