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The Neurobiological Foundations of Treatment Response in Children with Developmental Dyslexia: An exploratory study

The Neurobiological Foundations of Treatment Response in Children with Developmental Dyslexia: An exploratory study - Dyslexia treatment

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON42443
Enrollment
72
Registered
2016-01-05
Start date
2016-06-15
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Leerstoornis Dyslexia

Interventions

None listed

Sponsors

Radboud Universiteit Nijmegen
Lead Sponsor

Eligibility

Age
2 Years to 17 Years

Inclusion criteria

Inclusion criteria: Dyslexic children - 11-13 years of age - Children with dyslexia must have completed a DD treatment program according to the Dutch nationally standardized protocol (see Blomert, 2006) - Speak Dutch as their first language Control group - 11-13 years of age or - 8-10 years of age - No diagnosis of dyslexia - Speak Dutch as their first language

Exclusion criteria

Exclusion criteria: - The participant has developmental dyslexia, but has not (yet) finished a DD treatment program. - Significant hearing or visual impairments not correctable by glasses or hearing aids - Any MRI counter-indications (e.g., metal implants, braces)

Design outcomes

Primary

MeasureTime frame
In the proposed study, brain activation patterns and structural measures of the connectivity of the brain are the dependent variables. We are particularly interested in the neural correlates of treatment response and whether and how this resembles or differs from age- and reading matched controls.

Secondary

MeasureTime frame
On a behavioural level, we will measure reading accuracy and fluency, phonological awareness capacity, and response to online altered auditory feedback (as a measure of speech perception/production interactions).

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)