Multiple Sclerosis
Conditions
Interventions
The intervention group will participate in a standardized dance program, 2
times a week, 60 minutes per lesson. The control group does not participate in
any intervention but will be on a waiting li
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Clinically definite MS - Age between 18-65 years - Meet safety criteria to undergo MRI examination - Sufficient motor skills (maximum EDSS-score of 5.0) - Mild cognitive impairment
Exclusion criteria
Exclusion criteria: MS-patients will be excluded if they: - Are younger than 18 years - Have comorbid neurological (other than MS) or psychiatric diseases - Have a history of alcohol or drugs abuse - Have relapses for at least 4 weeks prior to examination - Used corticosteroids 4 weeks before the first measurement - Do not meet the criteria for an MRI-scan
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain activity, brain connectivity and white matter integrity (MRI) of the whole brain and of the hippocampus in particular. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Subjective well-being (quality of life, anxiety, depression questionnaires; secundary parameter); 2) Objective cognitive performance (neuropsychological assessment); in particular (visual) memory (explorative parameter); 3) Physical functioning (mobility, walking function; explorative parameter) | — |
Countries
Netherlands
Outcome results
None listed