The role of theta/delta activity during decision making: a transcranial alternating current study

The role of theta/delta activity during decision making: a transcranial alternating current study - Theta/delta tACS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON42345

Enrollment

Registered

2015-08-04

Start date

2016-02-01

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Niet van toepassing - onderzoek bij gezonde vrijwilligers Niet van toepassing

Interventions

Transcranial alternating current stimulation (tACS) will be delivered by a battery-driven electric current stimulator (Eldith DC Stimulator (CE 0118), Ilmenau) using a pair of electrodes: (1) active

(2) reference electrode over the central part of the head (100 cm^2). Stimulation will be delivered for 12 minutes before a social conformity task. Stimulation comprises either: (1) active delta tAC

1 mA)

(2) active theta tACS (5 Hz

1 mA)

or (3) placebo (sham) tACS (0 mA).

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Between 18-35 years of age years; Right-handed; Non-smoking; Normal or corrected-to-normal vision; Willingness and ability to give written informed consent and willingness and ability to understand the nature and content, to participate and to comply with the study requirements.

Exclusion criteria

Exclusion criteria: (1) Average use of more than 3 alcoholic beverages daily; (2) Use of psychotropic medication or recreational drugs; (3) Skin disease; (4) Pregnancy; (5) Serious head trauma or brain surgery; (6) Neurological or psychiatric disorders; (7) Large or ferromagnetic metal parts in the head (except for a dental wire); (8) Implanted cardiac pacemaker or neurostimulator; (9) Participation in a NBS study in the past 28 days; (10) Previous participation in 10 or more NBS studies.

Design outcomes

Primary

Measure	Time frame
Primary research outcome: Conformity to different social cues during a decision task with fictitious monetary reward and punishment after application of tACS.	—

Secondary

Measure	Time frame
Secondary research outcome: (1) TACS-induced behavioural changes in the decision task will be correlated with participants' scores on the BIS/BAS inventory. (2) Change in the rest electroencephalogram (EEG) after tACS. (3) the effect of reward and punishment on feedback related negativity (FRN) and late positive potential (LPP).	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)