Skip to content

The effects of a single administration of a moderate dose of caffeine on cognitive control and spontaneous EEG theta/beta ratio

The effects of a single administration of a moderate dose of caffeine on cognitive control and spontaneous EEG theta/beta ratio - Caffeine and theta/beta ratio

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON42339
Enrollment
40
Registered
2016-04-20
Start date
2016-05-10
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gezonde studenten Not relevant

Interventions

Participants will visit the lab three times. In two lab sessions, separated by one week, participants will orally consume one capsule containing 200mg of pure caffeine (a similar amount of caffeine

Sponsors

Universiteit Leiden
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Female - Age 18-25 years - Consuming less than 100mg of caffeine (about one cup of coffee) per day on average - Fluent in Dutch language

Exclusion criteria

Exclusion criteria: - Severe physical or psychological morbidity that would adversely affect participation - Habitual smoking - Use of psychopharmaceutics

Design outcomes

Primary

MeasureTime frame
a) The change in performance (as measured with reaction times; RTs) on two cognitive tasks (n-back task & switch task) after caffeine consumption, relative to placebo consumption. We expect performance to improve (RTs to decrease) after caffeine consumption. b) The change in the ratio between EEG measured theta and beta oscillations after caffeine consumption (relative to placebo consumption). We expect theta/beta ratio to decrease after caffeine consumption, thereby mediating the effects of caffeine on cognitive performance.

Secondary

MeasureTime frame
a) The moderating effects of baseline dopamine activity (measured with baseline spontaneous eye blink rates and theta/beta ratio) on the effects of caffeine on cognition. b) The possible confounding effects of self-reported ADHD symptoms, sleepiness, and anxiety on the effects of caffeine on cognition.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)