Cognitive function and uremic toxins in patients with severe renal failure: a pilot study

Cognitive function and uremic toxins in patients with severe renal failure: a pilot study - Cognitive function and uremic toxins

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42335

Enrollment

Registered

2015-08-13

Start date

2015-12-11

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cognitive disorders Cognitive impairment

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Patients with CKD and receiving a living kidney transplantation within 4-6 weeks - Patient with CKD, dialysis dependent - Patient with low eGFR (eGFR = 18 years old - Written informed consent for study

Exclusion criteria

Exclusion criteria: - Any other (neurological) disorder which may impact cognitive function - Evident cerebrovascular diseases - Presence of acute or chronic psychosis, evident depression, severe learning disabilities - Major visual or hearing impairment - Not fluent in written and spoken Dutch - Inability to provide informed consent

Design outcomes

Primary

Measure	Time frame
1. Differences in cognitive test performances with respect to validated referenced values in the 3 different study groeps.	—

Secondary

Measure	Time frame
1. The differences in test scores between the 3 consecutive neuropsychological assessments. 2. The difference in uremic toxin concentration before and after kidney transplantation.	—

Countries

Netherlands

Outcome results