Prediction of persisting pain following breastcancer surgery by psycho-somato-sensory profiling

Prediction of persisting pain following breastcancer surgery by psycho-somato-sensory profiling - Prediction of persisting pain following breast cancer surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42323

Enrollment

390

Registered

2015-12-01

Start date

2015-12-01

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain following breast cancer surgery Postmastectomy pain

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Female patients undergoing a mastectomy or breast saving surgery as a primary treatment for breast cancer or the prevention of it.

Exclusion criteria

Exclusion criteria: Metastatic disease Secondary breast surgery Thoracotomy in the past Severe angina pectoris Not providing informed consent Insufficient knowledge of Dutch

Design outcomes

Primary

Measure	Time frame
Incidence and predictors of pain in the operated area one year after breast surgery for cancer with an intensity > NRS 3	—

Secondary

Measure	Time frame
Intensity and pathophysiology of PMPS and the impairment caused by this pain. Pain intensity will be based on the Brief Pain Inventory (BPI). Pain impairment will be measured with the Pain Disability Index (PDI). Other study parameters surgical treatment (kind of breast surgery, lymph node- and nerve handling) breast reconstruction (technique), surgical complications, details anesthesiological management postoperative pain intensity neurophysiological profile: quantitative sensory testing (QST), conditiones pain modulation (CPM) adjuvant oncological therapies: chemotherapy, hormonal therapy and radiation therapy Comorbidity, pre-existing local and other chronic pain complaints age BMI psycho-social variables: marital state, education, employment, quality of life, anxiety, patient expectations, fear of recurrence, pain catastrophizing, dispositional optimism and depression.	—

Measure

Time frame

Intensity and pathophysiology of PMPS and the impairment caused by this pain. Pain intensity will be based on the Brief Pain Inventory (BPI). Pain impairment will be measured with the Pain Disability Index (PDI). Other study parameters surgical treatment (kind of breast surgery, lymph node- and nerve handling) breast reconstruction (technique), surgical complications, details anesthesiological management postoperative pain intensity neurophysiological profile: quantitative sensory testing (QST), conditiones pain modulation (CPM) adjuvant oncological therapies: chemotherapy, hormonal therapy and radiation therapy Comorbidity, pre-existing local and other chronic pain complaints age BMI psycho-social variables: marital state, education, employment, quality of life, anxiety, patient expectations, fear of recurrence, pain catastrophizing, dispositional optimism and depression.

—

Countries

Netherlands

Outcome results