osteoporosis vertebral fracture
Conditions
Interventions
osteoporosis
quality of life
sagittal balance
vertebral compression fractures
Sponsors
Diakonessenhuis Utrecht
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: male and female patients aged 50 years or older, fracture of the thoracal resp lumbal spine, fracture less than one week old, low-energy trauma, signed informed consent
Exclusion criteria
Exclusion criteria: neurologic deficit, active cancer, psychiatric or mental disease, insufficient cognitive or language skills to complete questionnaires
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study endpoint is the functional outcome one year after an OVCF, measured by pain level and quality of life. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sagittale balance, measured on X-rays of total spine Mineral bone density will be measured by DXA (mg per cm2, T-score) and finite element analysis of quantitative CT scans will be conducted to measure volumetric BMD (mg per m3). Quality of life after three and six months Physical activity, Accelerometer-based measurements of movement | — |
Countries
The Netherlands
Outcome results
None listed