Cross-sectional study on plasma levels of activated protein C and related plasma proteins in Factor V Leiden and Prothrombin Mutation carriers

Cross-sectional study on plasma levels of activated protein C and related plasma proteins in Factor V Leiden and Prothrombin Mutation carriers - APC thrombophilia study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42226

Enrollment

100

Registered

2015-02-24

Start date

2015-04-21

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mutations that increase the risk of blood clots Prothrombotic mutations

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Population 1: healthy, 18 years or older, thrombophilia carriership (cases). Population 2: healthy, 18 years or older, pregnant, thrombophilia carriership (cases)

Exclusion criteria

Exclusion criteria: Medication that influences secondary hemostasis, known risk factors for venous thromboembolism, current pregnancy complications.

Design outcomes

Primary

Measure	Time frame
Plasma levels of APC and related plasma proteins.	—

Secondary

Measure	Time frame
Plasma levels of proteins related to angiogenic pathways. The correlation between the APC plasma levels according to conventional and the novel assay.	—

Countries

Netherlands

Outcome results