Effect van nitraatsuppletie op plasma nitriet waarden en bloeddruk (niet aandoenings gerelateerd) blood pressure Pharmacokinetics
Conditions
Interventions
Acute bolus ingestion containing 800 mg (12.9 mmol) nitrate in the form of
NaNO3- in a water solution, red beetroot juice, a spinach based beverage, or a
rocket salad based beverage. All 4 trials wi
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Healthy (not being diagnosed with a cardiovascular or metabolic disease and/or no presence of mental/psychological conditions) - 18 - 45 years of age - 18.5 1 h a week)
Exclusion criteria
Exclusion criteria: - Use of medication - Smoking - Currently supplementing diet with nitrate - Lactose intolerance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary parameter will be plasma levels of nitrite following an acute dose of nitrate from different sources. | — |
Secondary
| Measure | Time frame |
|---|---|
| - plasma concentration of nitrate, glucose and free fatty acids - resting blood pressure - gastro-intestinal tolerance questionnaire and questions about the palatability of the drinks | — |
Countries
Netherlands
Outcome results
None listed