Sarcopenia
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Geriatric outpatients: Elderly referred to the geriatric outpatient clinic of the Center of Geriatric Medicine Amsterdam (COGA), VU University Medical Center Amsterdam.;Healthy age matched controls: Elderly attending social or group activitties, being medically stable, free from major diseases.
Exclusion criteria
Exclusion criteria: Geriatric outpatients: No exclusion criteria will be applied.;Healthy age matched controls: Exclusion criteria from the European MYOAGE study will be applied; dependent living status, the inability to walk a distance of 250 meter, morbidity, immobilization, the use of specific medication, orthopedic surgery , and participation in athletic events.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary study parameter is muscle mass on which the sample size calculation was made. - The correlation of muscle mass with the secondary study parameters in geriatric outpatients. - The difference in muscle mass between geriatric outpatients and healthy age matched controls. | — |
Secondary
| Measure | Time frame |
|---|---|
| Muscle-related parameters: - Muscle strength - Physical performance Energy expenditure: - Basal metabolic rate - Actual physical activity Nutritional status: - Energy intake - Protein status Cellular senescence: - Senescent cells | — |
Countries
Netherlands