Effects of immunosuppressive agents on innate immunity in renal transplant patients

Effects of immunosuppressive agents on innate immunity in renal transplant patients - Immunosuppressive agents and innate immunity

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42130

Enrollment

105

Registered

2015-03-09

Start date

2016-02-01

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pyelonefritis urinary tract infection

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients have to be older than 18 years Patients have to be at least 6 month post renal transplant Clinically stable patients at the time of blood donation (without bacterial infection) > 3month on CNi + MMF or mTORi + MMF as immunosuppressive regime

Exclusion criteria

Exclusion criteria: zie vorige

Design outcomes

Primary

Measure	Time frame
Expression pattern of TLR4 mediators in cells isolated from blood of renal transplant patients who receive immunosuppressive drugs	—

Secondary

Measure	Time frame
Release of cytokines by ex-vivo stimulated cells with LPS	—

Countries

Netherlands

Outcome results