Pyrosis reflux
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age 18 * 50 years Frequent physical activity: at least 10 km of running a week
Exclusion criteria
Exclusion criteria: History of peptic ulcer disease Known Barrett*s oesophagus History of GI cancer GI tract surgery (except appendectomy) Use of drugs that affect GI function Other organic gastro-intestinal diseases or functional disorders such as irritable bowel syndrome or functional dyspepsia Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total reflux time (% of time with esophageal pH | — |
Secondary
| Measure | Time frame |
|---|---|
| - Total number of reflux episodes (acid and non-acid) - LES function - Intra-abdominal pressure - Esophageal motility - Frequency of TLESRs - Frequency of TLESRs with reflux - Frequency of non-TLESR reflux events - Reflux symptoms (heartburn, regurgitation) | — |
Countries
Netherlands
Outcome results
None listed