anhedonia loss of pleasure
Conditions
Interventions
The group of 60 individuals without anhedonia will serve as a control group
only during the observation month of the diary study, in which no intervention
takes place, and will not partake in the in
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Screening;- 18-24 years old - Fluent in Dutch;Intervention;Anhedonic group: - persistent (> 2 months) anhedonia - willing to perform a tandem skydive;Control group: - no anhedonia - willing to perform a tandem skydive
Exclusion criteria
Exclusion criteria: Intervention - Inability to keep an electronic diary three times a day - Current professional treatment for psychiatric problems - Current use of psychopharmaca - Epilepsy - Pregnancy - Conditions that make it impossible to be attached to the tandemmaster (loose prostheses) - Height of more than 2 meters - Weight of more than 95 kg - Inability to raise ones legs 90 degrees (needed for save landing after tandem skydive) - Significant visual or hearing impairments - Previous experience with skydiving, bungee jumping, or base jumping - Cardiovascular complaints/problems
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study endpoint of the intervention study is the level of pleasure, as measured in the daily questionnaires. We will follow two approaches to evaluate the effectiveness of the intervention. First, we will examine each individual series of observations to assess individual response patterns in pleasure scores. Second, to explore group-level patterns of change, we will evaluate possible differences between intervention groups in daily-reported pleasure. | — |
Secondary
| Measure | Time frame |
|---|---|
| Intervention study: As a secondary endpoint we will explore possible differences between intervention groups in monthly-reported pleasure in different dimensions (i.e., motivational, anticipatory, and consummatory dimensions) and different domains (i.e., physical, sexual, social, aesthetic, and intellectual domains).In addition to the level of pleasure endpoints, the effects of the intervention will also be examined with regard to changes in blood and saliva levels of potential biomarkers. Blood samples are taken at six different time points and saliva samples are taken four times on the day of the skydive intervention. Other secondary parameters that could affect the effectiveness of the intervention are (epi)genetic factors, perceived physical and mental health, and positive and negative affect. Furthermore, the extent to which the lifestyle advice will lead to actual lifestyle change will be investigated by comparing the level and slope of the lifestyle variables in the pre- and post-intervention period. Furthermore, the dairy study will provide ample opportunity to examine the relations between mental and physical health, substance intake (i.e. food, alcohol, coffee, drugs) and sleep quality. Survey: Apart from as a screening tool, data from the survey will also be used to elucidate the various faces of pleasure loss, how often and in which combinations they occur in the general population, and how they relate to other variables such as lifestyle factors, (mental) health problems, personality, self-efficacy, emotion recognition skills and social position. | — |
Countries
Netherlands
Outcome results
None listed