Prime physiological determinants associated with peak power and endurance cycling performance

Prime physiological determinants associated with peak power and endurance cycling performance - Physiology of cycling performance

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42016

Enrollment

Registered

2014-06-16

Start date

2014-10-28

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

geen aandoeningen -

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Male, age 18-45 year Trained track or road cyclists (VO2-max > 55ml/kg/min) Low risk / healthy: based on the outcome of the anamnesis form

Exclusion criteria

Exclusion criteria: Allergic to local anesthetic Female Age 45 year VO2-max

Design outcomes

Primary

Measure	Time frame
The primary outcome of this study is the peak power and endurance cycling performance of the cyclist (POpeak during Wingate and VO2-max). These two outcome measures will be related to muscle contractile characteristics (i.e. mitochondrial density, myoglobin concentration, capillary density, muscle fiber size and fiber type).	—

Secondary

Measure	Time frame
The secondary outcome parameter of this study is peak power and endurance of the cyclist (POpeak during a vertical jump and POmean during a 15,000m time trial). These two outcome measures will be related to muscle contractile characteristics (i.e. mitochondrial density, myoglobin concentration, capillary density, muscle fiber size and fiber type). The next secondary outcome measure are the non-invasive measurements of muscle oxidative metabolism (i.e. TSI, O2Hb and HHb, as measured by Near Infrared Spectroscopy) and muscle architecture (muscle cross-sectional area as measured by ultra-sound). These outcome variables are compared to invasive measurements of oxidative metabolism (i.e. mitochondrial density, myoglobin concentration, capillary density) and muscle architecture (i.e. fiber size). The last secondary outcome measure is the remaining parameters of peak power and endurance performance of the cyclist (POpeak, POmean, time-to-peak and fatigue index during Wingate, and POpeak, POmean and jump height during vertical jump, P-VO2-max, POmean and finish time 15,000m time trial). These outcome measures are related to mechanical gross efficiency, maximal voluntary knee extension torque and anthropometric, cardio-respiratory, hematological and endocrine parameters.	—

Measure

Time frame

The secondary outcome parameter of this study is peak power and endurance of the cyclist (POpeak during a vertical jump and POmean during a 15,000m time trial). These two outcome measures will be related to muscle contractile characteristics (i.e. mitochondrial density, myoglobin concentration, capillary density, muscle fiber size and fiber type). The next secondary outcome measure are the non-invasive measurements of muscle oxidative metabolism (i.e. TSI, O2Hb and HHb, as measured by Near Infrared Spectroscopy) and muscle architecture (muscle cross-sectional area as measured by ultra-sound). These outcome variables are compared to invasive measurements of oxidative metabolism (i.e. mitochondrial density, myoglobin concentration, capillary density) and muscle architecture (i.e. fiber size). The last secondary outcome measure is the remaining parameters of peak power and endurance performance of the cyclist (POpeak, POmean, time-to-peak and fatigue index during Wingate, and POpeak, POmean and jump height during vertical jump, P-VO2-max, POmean and finish time 15,000m time trial). These outcome measures are related to mechanical gross efficiency, maximal voluntary knee extension torque and anthropometric, cardio-respiratory, hematological and endocrine parameters.

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Countries

Netherlands

Outcome results