atopic dermatitis atopic eczema
Conditions
Interventions
Each patient is assigned a randomization number according to a computer
generated randomization. Randomization will be performed with a 1:1 allocation.
One group will shower once daily every day acc
the other group will shower once weekly according to a standard
protocol for 4 weeks. All patients will use emollients daily and will be
allowed to continue topical medication (except tar ointments)
atopic dermatitis
water
Sponsors
Academisch Medisch Centrum
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: Male or female patients with atopic dermatitis (AD) according to the UK working party criteria Age 4-12 years Mild to moderate AD (objective SCORAD
Exclusion criteria
Exclusion criteria: Active skin infection requiring antibiotic treatment Systemic immunomodulatory treatment (for AD or other diseases) Intolerance to Vaseline paraffin ANA Unwillingness to use Vaseline paraffin ANA as sole emollient Usage of tar ointments Usage of thin bleach baths Performance of water sports (swimming etc) more than once a week
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of change in objective SCORAD from week 4 compared to week 0 between procedure groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of change in Eczema Area and Severity Index (EASI), quality of life, AD symptoms, transepidermal water loss, skin capacitance, natural moisturizing factors and skin lipids in tape strips at week 4 compared to week 0 between procedure groups. Used amounts of topical medication and Vaseline paraffin ANA and patient*s preference for once weekly vs daily showering at week 4 will be compared between procedure groups. The change in objective SCORAD from week 4 compared to week 0 will be compared between procedure groups, stratified by mild vs moderate AD, and stratified by light skin types (1, 2, 3) vs dark skin types (4, 5, 6). | — |
Countries
The Netherlands
Outcome results
None listed