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The effect of leucine and nandrolone decanoate supplementation on muscle loss during immobilisation

The effect of leucine and nandrolone decanoate supplementation on muscle loss during immobilisation - nandrolone and leucine during immobilisation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON41995
Enrollment
60
Registered
2015-04-13
Start date
2015-09-07
Completion date
Unknown
Last updated
2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disuse atrophy muscle loss

Interventions

One leg will be immobilized at a 30 degree knee joint angle of flexion for 7 days by means of a full leg cast. In addition, participants will ad random be allocated to the leucine group or nandrolon

Sponsors

Universiteit Maastricht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Male Aged from 18-35 years 18.5

Exclusion criteria

Exclusion criteria: (Family) history of thromboembolic events Smoking Recent surgery

Design outcomes

Primary

MeasureTime frame
Quadriceps CSA

Secondary

MeasureTime frame
whole upper leg muscle CSA muscle fiber type specific CSA muscle fiber type-specific satellite cell content 1RM muscle strength

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)