brein activaties doormiddel van fMRI onderzoek maar is geen aandoening brain activations using fMRI research when people infer emotions
Conditions
Interventions
Sponsors
Erasmus Universiteit Rotterdam
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: All subjects need to be female healthy adults (age 20-50) with self-reported normal or corrected-to-normal vision and normal hearing.
Exclusion criteria
Exclusion criteria: Individuals with a history of neurological or psychiatric disease or current medication affecting the central nervous system (CNS) will be excluded from the experiment. Individuals having ferromagnetic objects in the body will not be allowed to participate. In addition, individuals wearing jewelry, metal objects, external prostheses, cards, keys, etc. will be asked to leave them in the locker outside the MRI scanner room. Subjects who refuse to comply will be excluded from the experiment. Moreover, participants will be asked to fill in safety instruction and screening forms (Example 3). Individuals who refuse to fill in the safety instruction and screening form or do not fully comply with the rules for safety MRI examination will not be allowed to do the experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main study parameters/endpoints: Behavioural Main behavioural parameter will be the inferring accuracy which will be calculated as the percentage of items correctly identified as preferred versus not preferred choice. As a second measure of inferring accuracy we will calculate Pearson correlation between observers* and consumers* ratings on choice preference as well as between consumers* and friend*s ratings on subjective feelings. Self-assessment manikin (SAM) scale will be used to measure emotions (subjective feelings) valance and arousal in relations to visual stimuli. Consumers* emotional expressiveness will be assessed by the observer using 7-likert scale. Consumers* choice preferences will be assessed by means of 7-likert scale. Neuroimaging For the observer neural activity will be measured with functional magnetic resonance imaging (fMRI) derived from blood-oxygenation-level-dependent (BOLD) signal in regions-of-interest (ROI) from subjects performing experimental task. Main study parameter will be the level of inter-subject correlation (ISC) across conditions and in relation to task performance. For the consumer and his friend neural synchronization will be assessed with electroencephalogram (EEG). Again, main study parameter will be the level of inter-subject correlation (ISC) across trials in relation to participant*s self-assessed subjective feelings. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not applicable. | — |
Countries
The Netherlands
Outcome results
None listed