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Train the sedentary brain: move smart to reduce the risk of dementia;Sub study: Alternating aerobic and strength exercise in APOEe4 carriers and non-carriers in early stage dementia: effects and dose-response relation

Train the sedentary brain: move smart to reduce the risk of dementia;Sub study: Alternating aerobic and strength exercise in APOEe4 carriers and non-carriers in early stage dementia: effects and dose-response relation - Aerobic and strength exercise in dementia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON41982
Enrollment
118
Registered
2015-02-24
Start date
2015-04-01
Completion date
Unknown
Last updated
2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dementia

Interventions

The experimental group receives alternating aerobic-strength exercise, 3 sessions per week for 30 minutes, 12 weeks with low intensity and 12 weeks with high intensity. The control group receives st

Sponsors

Universitair Medisch Centrum Groningen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age >= 65 years Diagnosis of dementia Visiting daycare at least three times a week Able to perform the Timed Up & Go Test with or without assistive device Mini Mental State Examination (Folstein and Folstein 1975) score > 10.

Exclusion criteria

Exclusion criteria: Wheelchair bound Cardiovascular problems that limit physical activity Brain trauma Epilepsy Progressive or terminal disease Depression History of alcoholism Severe visual problems Severe auditory problems Problems with the Dutch language Mental incompetence

Design outcomes

Primary

MeasureTime frame
Main outcome measure is cognitive function, measured with neuropsychological tests.

Secondary

MeasureTime frame
Secondary outcome measures are physical functioning measured with performance-based field tests, and ADLS, mood and quality of life, measured by questionnaire.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)