Dry eye diseases tearfilm disorders
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria persons without dry eyes: age > 18 years, never have symptoms of dry eyes (scored at the Mcmonnies questionnaire) , Osmolarity 18 years, symptoms of dry eyes (scored on the Mcmonnies questionnairre), Osmolarity > 308.
Exclusion criteria
Exclusion criteria: Exclusion criteria for persons with and without dry eye symptoms: eye surgery, including refractive and plastiv surgery, herpes simpex infections, allergic constituion, antiglaucoma therapy, contact lens wearers, visual acuity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The evaporation rate, and the dew point, Sialic acid concentration, number of goblet cells. | — |
Secondary
| Measure | Time frame |
|---|---|
| subjective extent to which the patient experiences symptoms (McMonnies questionnaire, VAS scale), the Schirmer test. | — |
Countries
The Netherlands