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THE EFFECT OF NIACINAMIDE SUPPLEMENTATION ON PHOSPHATE CONCENTATIONS IN DIALYSIS PATIENTS.

THE EFFECT OF NIACINAMIDE SUPPLEMENTATION ON PHOSPHATE CONCENTATIONS IN DIALYSIS PATIENTS. - the DiaNia-study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON41924
Enrollment
30
Registered
2016-06-20
Start date
2015-07-01
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

high phosphate level hyperphospatemia

Interventions

During 12 weeks intake of daily niacinamide followed by placebo daily during 12 weeks or reverse.

Sponsors

Ziekenhuis Gelderse Vallei
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Hemodialysis patients - Adults (* 18 year) - Stable dialysis state (at least 6 months hemodialysis ) as measured at baseline

Exclusion criteria

Exclusion criteria: - Severely malnourished patients as diagnosed by the dietitian - Patients who dialyse at night in-hospital - Language barrier

Design outcomes

Primary

MeasureTime frame
The main study parameter is the serum phosphate concentrations in week 8 and 12.

Secondary

MeasureTime frame
Other study parameters are compliance to phosphate binders and supplement-related complaints such as nausea, diarrhea, flushing and itchiness that leads to dropout.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)