Subcellular components and multi-drug resistance in epithelial ovarian carcinoma

Subcellular components and multi-drug resistance in epithelial ovarian carcinoma - SCP&MDR

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON41885

Enrollment

Registered

2015-02-05

Start date

2014-12-22

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ovarian cancer Ovarian carcinoma

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with untreated epithelial ovarian cancer, stage III or IV.

Exclusion criteria

Exclusion criteria: Patients deprived from ability to decide for participation on her own

Design outcomes

Primary

Measure	Time frame
In this protocol, various parameters are to be distinguished: - Differences in concentration of ctDNA copy numbers and specific DNA fragments in EOC, EOC responding adequately to chemotherapy and EOC with chemotherapy resistance. - Differences in concentration of miRNA and specific miRNAs in EOC, EOC responding adequately to chemotherapy and EOC with chemotherapy resistance. - Differences in concentration and characteristics of EVs from patients with EOC, EOC responding adequately to chemotherapy and EOC with chemotherapy resistance.	—

Measure

Time frame

In this protocol, various parameters are to be distinguished: - Differences in concentration of ctDNA copy numbers and specific DNA fragments in EOC, EOC responding adequately to chemotherapy and EOC with chemotherapy resistance. - Differences in concentration of miRNA and specific miRNAs in EOC, EOC responding adequately to chemotherapy and EOC with chemotherapy resistance. - Differences in concentration and characteristics of EVs from patients with EOC, EOC responding adequately to chemotherapy and EOC with chemotherapy resistance.

—

Secondary

Measure	Time frame
Not applicable.	—

Countries

Netherlands

Outcome results