NEUROCONTROL * ASSESSMENT AND STIMULATION: integrative assessment of motor (dys)function in neurological disorders

NEUROCONTROL * ASSESSMENT AND STIMULATION: integrative assessment of motor (dys)function in neurological disorders - NEURAS-IMA

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON41873

Enrollment

171

Registered

2014-06-12

Start date

2015-02-04

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebrovascular accident (CVA stroke)

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: General: 18 years or older, male/female, have command of the Dutch language Additional for Stroke: survivor of a cerebrovascular accident (stroke) Additional for PD: Diagnosed with PD according to the UK PD Brain Bank criteria Additional for healthy controls: normal function of both arms, normal or corrected to normal vision

Exclusion criteria

Exclusion criteria: General: * (additional) neurological diseases and/or orthopedic problems interfering with hand/arm function * unable to comply with the protocol, i.e. insufficient general fitness or cognitive/communicative inability to understand instructions and participate in the measurement;Additional for stroke: *

Design outcomes

Secondary

Measure	Time frame
Clinical test scores. For stroke patients:Fugl-Meyer (upper extremity), Action Research Arm Test, Ashworth score, Erasmus modification of the Nottingham Sensory Assessment (upper extremity), Line Bisection Task, Montreal Cognitive Assessment and Nottingham Extended Activities of Daily Living) For PD patients: Movement Disorder Society version of the Unified Parkinson Disease Rating Scale (MDS-UPDRS), Questionnaire for Impulsive-Compulsive Disorders in Parkinsons Disease Rating Scale, the Scales for Outcomes in Parkinson*s Disease - Cognition (SCOPA-COG) and Psychiatric Components (SCOPA-PC), Beck Depression Inventory and Erasmus modification of the Nottingham Sensory Assessment (upper extremity)). Other study parameters: age, sex, education level, work, dominant side, (most) affected side, disease duration, pathology and history of treatment, current medication use (type and dose), Hoehn-Yahr stage (for PD patients), Bamford classification (for stroke patients), visual acuity, numeric rating scale for pain and perceived strain.	—

Measure

Time frame

Clinical test scores. For stroke patients:Fugl-Meyer (upper extremity), Action Research Arm Test, Ashworth score, Erasmus modification of the Nottingham Sensory Assessment (upper extremity), Line Bisection Task, Montreal Cognitive Assessment and Nottingham Extended Activities of Daily Living) For PD patients: Movement Disorder Society version of the Unified Parkinson Disease Rating Scale (MDS-UPDRS), Questionnaire for Impulsive-Compulsive Disorders in Parkinson*s Disease * Rating Scale, the Scales for Outcomes in Parkinson*s Disease - Cognition (SCOPA-COG) and Psychiatric Components (SCOPA-PC), Beck Depression Inventory and Erasmus modification of the Nottingham Sensory Assessment (upper extremity)). Other study parameters: age, sex, education level, work, dominant side, (most) affected side, disease duration, pathology and history of treatment, current medication use (type and dose), Hoehn-Yahr stage (for PD patients), Bamford classification (for stroke patients), visual acuity, numeric rating scale for pain and perceived strain.

—

Primary

Measure	Time frame
Kinematic parameters obtained by HR and MT (e.g., maximum active range of motion, accuracy, velocity and smoothness of goal-directed movements, performance on a visuo-motor tracking task), and neuromechanical and kinetic parameters obtained by HR (e.g., joint impedance, maximum voluntary torque, voluntary torque modulation accuracy and steadiness).	—

Countries

Netherlands

Outcome results