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Investigating inhibitory processes within the motor cortex during conflict resolution using transcranial magnetic stimulation

Investigating inhibitory processes within the motor cortex during conflict resolution using transcranial magnetic stimulation - Inhibition of M1 during conflict

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON41872
Enrollment
24
Registered
2014-06-23
Start date
2015-07-08
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neuroscientific research na

Interventions

Participants will receive a total of 864 trials. On half of the trials a single pulse of TMS will be applied, on the other half of trials two TMS pulses will be applied in quick succession.

Sponsors

Radboud Universiteit Nijmegen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Only healthy, competent, right-handed participants, 18-45 years old, with normal vision or corrected-to normal vision by means of contact lenses.

Exclusion criteria

Exclusion criteria: Serious head trauma or brain surgery - Large or ferromagnetic metal parts in the head (except for a dental wire) - Implanted cardiac pacemaker or neurostimulator - Pregnancy - Large of ferromagnetic metal parts in the body - Claustrophobia - Skin diseases at intended electrode sites - Disorders of vision (i.e., deviation from *normal or corrected-to-normal vision*) - History or current presence of any neurologic or psychiatric disease - Any prescribed medication that can alter cortical excitability (e.g. antiepileptics, tricyclic anti-depressives or benzodiazepines) or can have an influence on the participant*s vigilance or cognitive performance within two weeks prior to participation.

Design outcomes

Primary

MeasureTime frame
Changes in the amplitude of the MEP in response to single- and paired-pulse TMS (sICI) as a function of task condition (left or right hand response, conflict or no conflict trial).

Secondary

MeasureTime frame
behavioral outcome of choice RT task.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)