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Right Ventricular neurohormonal signalling in patients with Pulmonary Arterial Hypertension using Positron Emission Tomography

Right Ventricular neurohormonal signalling in patients with Pulmonary Arterial Hypertension using Positron Emission Tomography - RV neurohormonal signalling in PAH patients using PET

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON41856
Enrollment
19
Registered
2015-02-19
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

high blood pressure in the pulmonary vasculature Pulmonary Arterial Hypertension

Interventions

None listed

Sponsors

Vrije Universiteit Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients have to be diagnosed with IPAH of HPAH conform ESC/ERS guidelines (mPAP18 years. Adaptive patients are defined as patients with a RVEDVI 35%, measured 84 ml/m ² AND a RVEF 50 years of age

Exclusion criteria

Exclusion criteria: PAH patients:

Design outcomes

Primary

MeasureTime frame
The uptake of [11C]-HED and [11C]-CGP-12177 in the right ventricle of pulmonary arterial hypertension patients and healthy subjects to determine pre- and post-synaptic sympathetic nerve activity in various stages of disease.—

Secondary

MeasureTime frame
-—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)