algemeen gezondheidsparameters, biomarkers en voeding health parameters and biomarkers nutrition
Conditions
Interventions
Data Collection
Health
Nutritional Physiological Phenomena
self-quantification methodologies
Sponsors
TNO
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Employees or students that are active in the field of nutrition and/or biology and/or health (e.g. epidemiologists, dieticians, nutrition students and researchers) that have a basic knowledge of nutrition and/or human biology and are thus able to form a scientific judgement on his/her own health data; 2. good understanding of the English written language, since all communication is handled in English.
Exclusion criteria
Exclusion criteria: For any participant who matches the inclusion criteria, there are no exclusion criteria. The concept of the Nutrition Researcher Cohort is that research is performed on a *multiple N=1* basis, i.e. each participant provides his/her own health dataset and as such a wide range of healthy and possibly unhealthy subjects can participate. ;In the future, for the proposed research questions suggested by the participants of NRC and agreed in the management of the NRC, a selection may be made including/excluding part of the phenotypes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The open access Nutrition Researcher Cohort for gathering personal health data from nutrition researchers will be evaluated by determining compliance of participants with the research protocol. Compliance will be determined for self-quantification methods that all participants are expected to use, as well as the optional measures. Compliance of participants with the study protocol will also be compared between countries. User experiences with participating in the cohort and using self-quantification methods for monitoring their health will be assessed with a questionnaire on user-experience after one year. This questionnaire has not yet been finalized, as it is not yet clear which specific self-quantification methods will be included in the cohort. However, a format for this questionnaire has already been developed (F09). The questionnaire will encompass questions on the cohort in general, the used visualisations for personal data, usability of the self-quantification methods, the satisfaction of the user with the self-quantification methods and the effects of self-quantification on user behaviour. | — |
Secondary
| Measure | Time frame |
|---|---|
| Dependent on the quality, the data resulting from the self-quantification methods (including body weight, physical activity, food intake, blood glucose, blood pressure, resting heart rate, quality of sleep, cortisol in hair, epigenetics, etc.) will be analysed to identify changes in these health parameters over time. These self-quantification methods can be divided into two groups, namely the self-quantification methods that are mandatory for all participants and those that are optional. The first group of self-quantification methods include conventional non-invasive or minimally invasive measures, like body weight, waist circumference, blood pressure, fasting glucose and blood lipids with finger prick. The set of optional self-quantification methods, which are more complex or invasive methods, is not yet set. Which measurements will be offered to participants is dependent on funding. Examples of measurements that could be included are concentrations of biomarkers in blood, cortisol in hair/nail (as a biomarker for stress) clippings and epigenetic profile. The complete lists of mandatory and optional self-quantification measurements and the can be found in table 1-2, respectively table 3. Table 1 and 2 also contain the procedures that participants should use for each of the included measurements. Table 3 contains the required laboratory analysis methods and the intended labs. All subjects will also be asked to regularly fill out online-questionnaires on general health status, lifestyle (smoking, alcohol consumption), quality of sleep, stress, physical activity and quality of life (table 2). Which specific questionnaires will be used in this cohort, has not yet been decided on. However, sample questionnaires have been added to this protocol as an indication for the expected burden for participants (chapter 11). | — |
Countries
Austria, Belgium, Czechia, Denmark, Finland, France, Germany, Ireland, Italy, Netherlands, Sweden, Switzerland, United Kingdom, United States of America
Outcome results
None listed