Evaluation of hand function in patients with Duchenne muscular dystrophy, including an additional pilot study with a newly designed glove. An explorative study.

Evaluation of hand function in patients with Duchenne muscular dystrophy, including an additional pilot study with a newly designed glove. An explorative study. - Hand function in Duchenne.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON41821

Enrollment

Registered

2015-06-29

Start date

2015-10-26

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Duchenne disease Duchenne muscular dystrophy

Interventions

Activities

Disease course

Duchenne muscular dystrophy

Hand function

Eligibility

Age

2 Years to 64 Years

Inclusion criteria

Inclusion criteria: A DNA-established diagnosis of DMD Informed consent

Exclusion criteria

Exclusion criteria: Presence of other disabling disease(s) with (major) influence on strength, mobility or activities, especially concerning the hand. Unable to cooperate with or understand testing

Design outcomes

Primary

Measure	Time frame
The primary goal of this study is to examine the natural disease course in the hands of persons with DMD. We will evaluate two different levels of human functioning according to the International Classification of Functioning, Disability and Health (ICF) model; the dimension of body function and structures as well as the dimension of activities. To measure strength and function we will use the recently developed tools MyoPinch, MyoGrip and MOVIPLATE. To assess the presence of contractures we will measure range of motion using goniometry. To evaluate and describe activities we will use several instruments, including Brooke, MACS, PUL, Timed-TIHM and CUE. We will perform an additional pilot in 5 to 15 patients where we will measure hand kinematics with a recently designed glove (TU Twente).	—

Measure

Time frame

The primary goal of this study is to examine the natural disease course in the hands of persons with DMD. We will evaluate two different levels of human functioning according to the International Classification of Functioning, Disability and Health (ICF) model; the dimension of body function and structures as well as the dimension of activities. To measure strength and function we will use the recently developed tools MyoPinch, MyoGrip and MOVIPLATE. To assess the presence of contractures we will measure range of motion using goniometry. To evaluate and describe activities we will use several instruments, including Brooke, MACS, PUL, Timed-TIHM and CUE. We will perform an additional pilot in 5 to 15 patients where we will measure hand kinematics with a recently designed glove (TU Twente).

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Secondary

Measure	Time frame
Secondary goals of this study are to explore relations between these two levels, the possible difference between the dominant and non-dominant hand, and possible influence of posture and/or training or splints.	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)