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Defining lymphatic drainage of the liver segments in man

Defining lymphatic drainage of the liver segments in man - Segmental liver lymphatic drainage

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON41745
Enrollment
36
Registered
2015-09-30
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver tumor

Interventions

None listed

Sponsors

Universitair Medisch Centrum Utrecht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age > 18 years, capacitated/mentally competent persons, written informed consent, all patients undergoing partial hepatectomy for liver tumors in the UMC Utrecht can be included in this study.

Exclusion criteria

Exclusion criteria: - Patients undergoing open RFA for a liver tumor without partial hepatectomy will be excluded from this study. - Patients undergoing robotic- or laparoscopic partial hepatectomy will be excluded from this study. - Patients with a history of liver surgery including dissection of the hepatoduodenal ligament will be excluded from this study. - Known allergy for Blue Patente V®, in accordance with the SPC of Blue Patente V® version okt0132013/College ter Beoordeling van Geneesmiddelen - Minors or incapacitated subjects

Design outcomes

Primary

MeasureTime frame
- Define the pattern of lymphatic drainage and the draining lymph nodes from each of the liver segments (by peroperative lymphangiography and visual blue dye detection).

Secondary

MeasureTime frame
- Show that the human liver contains functional lymphatic vessels (by immunohistochemistry on resection specimens). - Show that the flow of lymphatic fluid follows segmental anatomy (by immunohistochemistry on resection specimens).

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)