'autoimmune encephalitis' and 'inflamed brain'
Conditions
Interventions
None listed
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: - Age under 18 years - Clinical profile fits one of the four groups: 1. limbic or cortical encephalitis, 2. new-onset seizures/status epilepticus without known cause, 3. acute encephalopathy with fever/inflammation-mediated status epilepticus or 4. acute-onset neuropsychiatric symptoms of basal ganglia dysfunction, like chorea . - No known cause, like a bacteria, virus, haemorrhage, stroke, genetic cause.
Exclusion criteria
Exclusion criteria: - 18 years or over - Patient and/ or legal representative is withholding informed consent - Patient objects after initial informed consent (see paragraph 8.3).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The characterization of new antibody-related clinical syndromes; 2. The frequency of the individual antibody-mediated syndromes in children; 3. The outcome of the individual antibody-mediated syndromes in children. | — |
Countries
Netherlands
Outcome results
None listed