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The LINC-study: LInking EDCs in maternal Nutrition and Child health

The LINC-study: LInking EDCs in maternal Nutrition and Child health - The LINC-study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON41667
Enrollment
500
Registered
2010-12-01
Start date
2011-01-17
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overgewicht obesity overweight

Interventions

None listed

Sponsors

Vrije Universiteit
Lead Sponsor

Eligibility

Age
2 Years to 99 Years

Inclusion criteria

Inclusion criteria: Healthy women eligible for participation should be less than twelve weeks pregnant at their first visit to the midwifery clinic. They should be able to fill out Dutch questionnaires. Incapacitated subjects will not be asked to participate.

Exclusion criteria

Exclusion criteria: Women with pre-eclampsia or twin pregnancies are excluded from further participation. Pre-eclampsia is defined as pregnancy-induced hypertension (1x diastolic pressure > 90 mmHg) in association with proteinuria (>0.3 g/day). Furthermore major congenital anomalies at birth will be reason for exclusion.

Design outcomes

Primary

MeasureTime frame
The main study endpoint are health outcomes in children, in particular obesity and neurobehavioral disorders at the age of 12 and 18 months, and 4 years, in relation to exposure markers of EDCs in cord blood.

Secondary

MeasureTime frame
Secundary parameters include health outcomes such as birth weight, height, waist circumference and head circumference. Furthermore outcomes such as asthma, allergies, neurodevelopment, behaviour, sleep and crying will be taken into account. All mentioned parameters will be related to exposure markers of EDCs in cord blood.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)