Overgewicht obesity overweight
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Healthy women eligible for participation should be less than twelve weeks pregnant at their first visit to the midwifery clinic. They should be able to fill out Dutch questionnaires. Incapacitated subjects will not be asked to participate.
Exclusion criteria
Exclusion criteria: Women with pre-eclampsia or twin pregnancies are excluded from further participation. Pre-eclampsia is defined as pregnancy-induced hypertension (1x diastolic pressure > 90 mmHg) in association with proteinuria (>0.3 g/day). Furthermore major congenital anomalies at birth will be reason for exclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study endpoint are health outcomes in children, in particular obesity and neurobehavioral disorders at the age of 12 and 18 months, and 4 years, in relation to exposure markers of EDCs in cord blood. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secundary parameters include health outcomes such as birth weight, height, waist circumference and head circumference. Furthermore outcomes such as asthma, allergies, neurodevelopment, behaviour, sleep and crying will be taken into account. All mentioned parameters will be related to exposure markers of EDCs in cord blood. | — |
Countries
Netherlands