ANTARCTICA: analysis using novel signaling pathway and 3-tesla imaging of arteriogenesis in chronic total occlusive coronary arteries

ANTARCTICA: analysis using novel signaling pathway and 3-tesla imaging of arteriogenesis in chronic total occlusive coronary arteries - ANTARCTICA

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON41624

Enrollment

Registered

2013-03-13

Start date

2013-10-17

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic total occlusion/ chronic total coronary occlusion

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: patients with a chronic total occlusion, in whom there is a clinical indication for CTO revascularization by means of PCI.

Exclusion criteria

Exclusion criteria: - known MRI contrast allergy -contra-indication for MRI - previous transmural infarction in the area of the CTO, diagnosed on ECG or MRI - - previous bypass cardiac surgery -cardiac arrhythmia limiting flow velocity measurements - congestive heart failure - - clinical or laboratory signs of acute or chronic inflammatory illness - impaired renal function (GFR

Design outcomes

Primary

Measure	Time frame
Correlation between the intracoronary derived parameters and cardiac MRI estimates of collateral coronary circulation.	—

Secondary

Measure	Time frame
Identification of genetic predispositions in patients with varying degrees of collateralization, in order to ultimately identify novel therapeutic targets.	—

Countries

Netherlands

Outcome results