Inflammation of the supporting tissues around a dental implant
Conditions
Interventions
Non-surgical treatment (mechanical cleaning of the implant surface) of
peri-implantitis with adjunctive use of systemic antibiotics (amoxicillin 375mg
and metronidazole 250mg three times a day for 7
Sponsors
Vrije Universiteit
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Dentate or edentate patients with at least one screw-type titanium implant;The implant should be in function for at least a period of 12 months;Peri-implant intraosseous defect with at least 3 mm depth measured from the neck. The extent of bone loss will be measured on the basis of peri-apical radiographs;Probing depth at the deepest site at least 5mm combined with bleeding and/or suppuration;Patient above 18 years of age;Psychological appropriateness;Signed Informed Consent obtained prior to start
Exclusion criteria
Exclusion criteria: Patient with a history of taking systemic antibiotics in the preceding 3 months;Patient allergic to penicillin (amoxicillin) or metronidazole ;Systemic diseases like diabetes, HIV, Sjögren, SLE;Use of NSAID*s in the last 4 weeks;Current pregnancy or lactating;Mobile implants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main outcome is the clinical attachment level (CAL). | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical parameters (pocket probing depth (PPD), bleeding on probing (BoP), plaque-accumulation and bone loss) and microbiological parameters. | — |
Countries
Netherlands
Outcome results
None listed