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Evaluation of the association between heart type fatty-acid binding proteins and high sensitive troponin and postoperative myocardial infarction in patients undergoing cardiac-surgery

Evaluation of the association between heart type fatty-acid binding proteins and high sensitive troponin and postoperative myocardial infarction in patients undergoing cardiac-surgery - Biomarkers for postoperative myocardial infarction in cardiac-surgery

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON41530
Enrollment
800
Registered
2015-03-25
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart attack myocardial infarction

Interventions

None listed

Sponsors

Universitair Medisch Centrum Utrecht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients over 18 years, undergoing isolated coronary artery bypass grafting (CABG), isolated valve surgery (aortic valve replacement, mitral valve repair or replacement) or combined CABG and valve surgery in the University Medical Center Utrecht

Exclusion criteria

Exclusion criteria: Emergency surgery, (suspected) sepsis or pulmonary embolism, renal failure (defined as Glomerular Filtration Rate

Design outcomes

Primary

MeasureTime frame
Measurements: From all patients* blood samples will be obtained before, during and after surgery to measure H-FABP en troponin levels. Other relevant information will be obtained from the Electronic Patient Record system and from the Anesthesia Information and Management System (AIMS). The primary end-point is myocardial infarction. The occurence of postoperative myocardial infarction is imported from the Board Heart interventions Netherlands registry (BHN registry). This particular item is standardly filled out for all cardiac surgery patients in this hospital by the department of cardiology independent of this research.

Secondary

MeasureTime frame
The secondary endpoint is mortality and hospital length of stay.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)