glucose variability mean absolute glucose change
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age 70 years or older. Admitted to the Geriatric trauma unit or to the department of Orthopaedics for hip surgery. An increased risk for the development of delirium using the Tergooi questionaire based on the Safety Management System theme 'vulerable older patients'. Inclusion within 24 hours after hospital admission. The patient speaks either Dutch or English. Patient must be able to give written informed consent.
Exclusion criteria
Exclusion criteria: Patients presenting with a diminished capacity to consent at admission. Patients with a diagnose of diabetes mellitus and/ or treated with oral antidiabetic drugs or insulin. Patients who are fed with parenteral nutrition during their hospital stay. Patients who are enrolled in a study with a medicinal product.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean absolute glucose change per hour (mmol/l/hour) | — |
Secondary
| Measure | Time frame |
|---|---|
| -The mean glucose concentration. -Glucose variability: standard devation of the mean glucose concentration and coefficient of variation and the mean glucose daily delta change - The presence of an isolated hypoglycemia or hyperglycemia. Potential risk factors: 1. Age 2. Gender 3. Body mass index 4. Cigarette smoking 5. Alcohol consumption 6. Introduction of diabetes mellituis treatment 7. Number of glucose influencing drugs. 8. Insulin concentration 9. Occurrence of a delirium. 10.Treatment with antipsychotic drugs. 11. Occurrence of any infection. 12. Nutrition. 13. Vitamin D concentration 14.Pain 15. Iron status 16. Serum triglycerides 17. Blood coagulation - Length of hospital admission - 6- months and 1 year mortality | — |
Countries
Netherlands