distal radius fracture wrist fracture
Conditions
Interventions
Group I receives standard care, i.e. start of administration of vitamin D3 12
weeks after fracture (control). Group II receives immediate administration of
daily calcium supplementation (1 Cacit bru
Sponsors
Viecuri Medisch Centrum voor Noord-Limburg
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Postmenopausal women older than 50 years who present themselves in clinic with a distal radius fracture due to a trauma. 2. Patients with a stable distal radius fracture type that is treated by cast immobilization. 3. Patients who understand the conditions of the study and are willing and able to comply with the scheduled biochemical and radiographic evaluations and the prescribed rehabilitation. 4. Patients who signed the Ethics Committee approved specific Informed Consent Form prior to inclusion.
Exclusion criteria
Exclusion criteria: 1. Patients who underwent surgery of the wrist or radius on a previous occasion on the same side or who need surgery this time. 2. Patients with active or suspected infection such as pneumonia or complicated urinary tract infection in the last 3 months. 3. Patients with malignancy or a pathological fracture in the last 12 months. 4. Patients with a neuromuscular or neurosensory deficit, e.g. Parkinson*s disease, which would limit the ability to assess the performance during the healing period. 5. Patients with known systemic or metabolic disorders leading to progressive bone deterioration, such as: hyperthyroidism, hyperparathyroidism, chronic kidney disease with eGFR
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are the changes in cortical and trabecular bone parameters that will be assessed by HR-pQCT and the changes in estimated bone strength and stiffness as calculated in the µFEA. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary study parameters are the standard clinical and functional outcomes that are obtained using the PRWE and QuickDASH questionnaires, the pain score using VAS and the range of motion assessment. Furthermore, blood serum markers for bone formation and resorption will be measured. | — |
Countries
Netherlands
Outcome results
None listed