diabetes
Conditions
Interventions
None listed
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: All surviving subjects who participated in 2006 - 2008 in the New Hoorn Study, since 2003/2004 in the RISC study or in 2005 - 2006 in the Hoorn meal study will be invited for this study.;Additional recruitment of subjects diagnosed with type 2 diabetes (to reach targets for DIRECT Study 2): patients diagnosed with type 2 diabetes for > 3 months and 35 and 50ml/min.;Participants also have to speak, read and write Dutch to participate.
Exclusion criteria
Exclusion criteria: Overall: Inability to give written informed consent (for instance due to dementia).;Study 1 and 2: pregnancy, lactation or a female planning to conceive within the study period, any significant medical reason for exclusion as determined by the investigator, unable to give written informed consent, unable to speak, read and/or write Dutch.;Study 1: Diabetes of any type, treatment with insulin sensitizing, glucose lowering, or other anti-diabetic drugs, HbA1c > 6,5%.;Study 2: type 1 diabetes, a previous HbA1c > 9.0%, prior treatment with insulin or an OHA other than metformin, BMI 50 kg/m2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the rate of glycaemic deterioration in people with type 2 diabetes and in people at high risk for type 2 diabetes, identifying fast and slow deteriorators. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not applicable. | — |
Countries
Netherlands
Outcome results
None listed