Determination whether the lack of functional AQP2 in kidneys of patients suffering from nephrogenic diabetes insipidus induces cyst formation

Determination whether the lack of functional AQP2 in kidneys of patients suffering from nephrogenic diabetes insipidus induces cyst formation - Determination of renal cyst formation in patients that lack functional AQP2

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON41471

Enrollment

Registered

2016-04-19

Start date

2016-12-21

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nephrogenic diabetes insipidus

Interventions

AQP2

Cyst

Kidney

Eligibility

Age

12 Years to 64 Years

Inclusion criteria

Inclusion criteria: Men and woman not known to be pregnant Congenital nephrogenic diabetes insipidus with a proven mutation of the AQP2 gene Age > 12 years

Exclusion criteria

Exclusion criteria: - Metal implants - Pacemaker - Intracranial aneurysmal vascular clips - Small metal particles/splinters - Cochlear implants - Old heart valve implants (the ones placed after 2001 are often MR-compatible) - Implants - Claustrophobia - All sorts of devices like bladder stimulators, neurostimulators and insulin pumps - Dental prosthesis/dental braces - Telemetric heart rate monitor - Metal tissue expanders - Known pregnancy

Design outcomes

Primary

Measure	Time frame
The main study parameter is the presence or absence of microcysts in kidneys.	—

Secondary

Measure	Time frame
-	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)