Improvement of Diagnostic mEthods for ALlergy assessment. Cashew allergy in children as a showcase (IDEAL study)

Improvement of Diagnostic mEthods for ALlergy assessment. Cashew allergy in children as a showcase (IDEAL study) - IDEAL

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON41456

Enrollment

200

Registered

2012-04-19

Start date

2012-05-20

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

food allergy IgE mediated allergy

Interventions

Double blind food challenge test, skin prick tests, blood draw, questionnaires.

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: Patients with a possible cashew nut allergy and a positive skin test (Histamine Equivalent Prick HEP > 0.2) or a positive CAP FEIA (> 0.35) with cashew nut extract. Age 2-17 (incl.) years. Written consent of parents (guardian) and -if 12 years and above- the patient.

Exclusion criteria

Exclusion criteria: Severe or uncontrolled asthma and/or recent ( 6). Immunological diseases, cardiovascular diseases or malignancy. Severe psychosocial problems. Not able to stop anti-histamine medication for a short period. Use of beta-blockers. The patient is allergic to one or more of the ingredients of the food matrix, unless a suitable substitute for the ingredient in question can be found.

Design outcomes

Primary

Measure	Time frame
Results of Mediator Release Assays in comparison with regular tests.	—

Secondary

Measure	Time frame
Adverse events, prevalence of allergy to cashew nuts. Genetic research.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)