Inflammatory injury of the lung after cardiac surgery

Inflammatory injury of the lung after cardiac surgery - INFLAME

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON41450

Enrollment

250

Registered

2011-09-27

Start date

2011-12-01

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Lung Injury Inflammatory induced pulmonary Injury

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adult patients scheduled for cardiac surgery

Exclusion criteria

Exclusion criteria: minor ermergency surgery not able to sign informed consent

Design outcomes

Primary

Measure	Time frame
Length of ICU-stay, length of hospital-stay, ICU-mortality, 30-day mortality	—

Secondary

Measure	Time frame
1. Prognostic: occurrence of ALI and ARDS, duration of mechanical ventilation, need for renal replacement therapy 2. Etiologic: levels and time course of markers of inflammation and ischemia-reperfusion in relation to the clinical course (such as AlI and ARDS, duration of mechanical ventilation, need for renal replacement therapy, ICU-stay, hospital-stay, ICU-mortality, 30-day mortality) particular in patients following complex heart surgery as opposed to low risk surgery 3. Methodologic: Investigate the value of collecting minimal invasive endobronchial samples in cardiac surgery patients.	—

Measure

Time frame

1. Prognostic: occurrence of ALI and ARDS, duration of mechanical ventilation, need for renal replacement therapy 2. Etiologic: levels and time course of markers of inflammation and ischemia-reperfusion in relation to the clinical course (such as AlI and ARDS, duration of mechanical ventilation, need for renal replacement therapy, ICU-stay, hospital-stay, ICU-mortality, 30-day mortality) particular in patients following complex heart surgery as opposed to low risk surgery 3. Methodologic: Investigate the value of collecting minimal invasive endobronchial samples in cardiac surgery patients.

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Countries

Netherlands

Outcome results