Health effects of eel consumption

Health effects of eel consumption - Fishermen study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON41358

Enrollment

108

Registered

2014-08-29

Start date

2015-02-24

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deze studie heeft niet direct betrekking op een aandoening. Not applicable

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Male Age between 40 and 70 years Consumption of eel >= 1x per month

Exclusion criteria

Exclusion criteria: There are no exclusion criteria.

Design outcomes

Primary

Measure	Time frame
The primary study outcome is the difference in serum POP concentrations in two groups of Dutch men consuming eel, namely the men consuming eel from polluted areas ('high* exposed) and those men consuming eel from clean areas (low exposed).	—

Secondary

Measure	Time frame
The secondary study outcomes are concentrations of thyroid hormones, retinol, insulin, glucose, cholesterol HDL, haematocrit, platelet count, testosterone and parameters for liver toxicity. In isolated peripheral blood mononuclear cells (PBMCs), DNA methylation patterns will be assessed. When a relationship between POP concentrations and DNA methylation is found, we will also measure gene expression levels.	—

Measure

Time frame

The secondary study outcomes are concentrations of thyroid hormones, retinol, insulin, glucose, cholesterol HDL, haematocrit, platelet count, testosterone and parameters for liver toxicity. In isolated peripheral blood mononuclear cells (PBMCs), DNA methylation patterns will be assessed. When a relationship between POP concentrations and DNA methylation is found, we will also measure gene expression levels.

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Countries

Netherlands

Outcome results