atrial fibrillation palpitations
Conditions
Interventions
None listed
Sponsors
Population Health Research Institute of Hamilton Health Sciences
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients will be eligible for inclusion if they provide written consent and meet both of the following: 1. Age * 65, plus: a. CHA2DS2-VASc score * 2 Or b. Obstructive sleep apnea (documented by polysomnography, ambulatory oximetry, positive Berlin Questionnaire or requiring the use of CPAP/BiPAP) Or c. BMI > 30;AND;2. Echocardiographic or biochemical evidence of increased risk of AF: a. Left atrial enlargement on a clinical echocardiograph at any time prior to enrolment (defined as LA volume * 58 ml or LA diameter of * 4.4 cm) Or b. Serum NT-ProBNP * 290 pg/mL
Exclusion criteria
Exclusion criteria: 1. Previously documented history of atrial fibrillation or atrial flutter, with an episode duration of at least 5 minutes 2. Current chronic treatment with oral anticoagulation (i.e., those on peri-operative prophylaxis would be eligible) 3. Patient with existing implanted pacemaker or defibrillator 4. Definitive plan for cardiac surgery in the next 6 months (patients who are having coronary angiography with a possibility of cardiac surgery are still eligible)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of patients with AF episodes longer than 5 minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine the relationship between left atrial volume (continuous variable) and the presence of AF. To evaluate potential predictors/markers of sub-acute AF including: troponin-T, NT-pro-BNP as well as echocardiographic parameters. A preliminary economic analysis of screening this patient population with an Implantable Cardiac Monitor. | — |
Countries
Netherlands
Outcome results
None listed