psychosis schizophrenia
Conditions
Interventions
None listed
Sponsors
Universiteit Maastricht
Eligibility
Age
12 Years to 99 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for the early psychosis group are: (i) the presence of attenuated psychotic symptoms, brief limited intermittent psychotic symptoms, genetic risk or the occurrence of a psychotic episode according to DSM-IV criteria, , (ii) age 15-35 years, (iii) sufficient knowledge of the Dutch language.;Inclusion criteria for the chronic psychosis group are: (i) life time occurrence of a psychotic episode according to DSM-IV criteria, (ii) illness onset > 6 years, (iii) age 25-55 years, (iv) sufficient knowledge of the Dutch language.
Exclusion criteria
Exclusion criteria: Exclusion criteria for the early psychosis group are: (i) onset of symptoms >2 years, (ii) frequent drug use (>2 times a week), (iii) Mental Retardation (IQ score 2 times a week), (iii) Mental Retardation (IQ score
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognition assessed in daily life Social cognition assessed in daily life Negative symptoms assessed in daily life Positive symptoms assessed in daily life Fluctuations in both cognition and social cognition in daily life and the influence of these fluctuations on positive and negative symptoms | — |
Secondary
| Measure | Time frame |
|---|---|
| Saliva samples will be collected for the purpose of molecular genetic studies. These studies aim at selecting SNPs (parts of the DNA where one nucleotide is different from one person to another) that contribute to the psychosis phenotype. | — |
Countries
Netherlands
Outcome results
None listed