Slaapstoornissen en -afwijkingen Parkinson's disease
Conditions
Interventions
Treatment consists of twice daily exposure to bright light
30 minutes in the
morning and evening for the time of three months. Halve of the patients are
exposed to high intensity light (10.000 Lux), the other halve to low intensity
light (200 Lux).
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Diagnosis of Parkinson's Disease Stably established on psychotropic medication (>4wk) or off medication for >4wk
Exclusion criteria
Exclusion criteria: psychosis mania suicidality medication inducing retinal photosensitivity retinopathy having had BLT before
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure is the percent change in score on the Hamilton Depression Rating Scale (HDRS) and Geriatric Depression Scale (GDS-30) between baseline and end of treatment (immediate effect) and between baseline and six months of follow-up (enduring effect). In addition, the Numbers Needed to Treat (NNT) on the basis of dichotomous treatment response (>50% reduction in HDRS-score immediately after treatment). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures are the change in score for measures of sleep (SCOPA-sleep), motor function (UPDRS-III), Quality of Life (WHOQOL-bref, ZBI) and circadian rhythms (actigraphy, cortisol morning curve and melatonin evening curve). | — |
Countries
Netherlands
Outcome results
None listed