Nexfin monitoring and laboratory testing in the per-and postoperative setting of major hepatectomy

Nexfin monitoring and laboratory testing in the per-and postoperative setting of major hepatectomy - NeMo study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON41251

Enrollment

Registered

2013-04-12

Start date

2013-10-03

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vochthouding in het lichaam tijdens en na een leverresectie decompensatio cordis overvulling

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: patients who will undergo a major hepatectomy

Exclusion criteria

Exclusion criteria: cirrhosis, renal failure, cardiac failure and cardiac arrythmias

Design outcomes

Primary

Measure	Time frame
Preoperative * Weight * Nexfin parameters: Stroke volume, cardiac output and cardiac index * 2x 24-hours urine sample for sodium, potassium and creatine excretion * 1x plasma sample antidiuretic hormone, aldosterone and renin Intraoperative * Fluid responsiveness after 250 ml fluid administration * Nexfin monitoring * Fluid balance and amount of fluids administered (ml.kg-1.h-1) Postoperative * 3 times a day Nexfin parameters: Stroke Volume, Cardiac Output and Cardiac index. The first measurement is in the morning before mobilization and after 2 minutes mobilization (out of bed; standing of sitting on a chair). * Daily body weight and ankle & abdominal girth * 2x 24-hour urine sample with sodium, potassium and creatine excretion * First 5 days at the ward: daily measurement of electrolytes sodium, potassium, bicarbonate and chloride. * Daily measurements of plasma concentrations aldosterone, renin and antidiuretic hormone will be done before mobilization and after 20 minutes mobilization.	—

Measure

Time frame

Preoperative * Weight * Nexfin parameters: Stroke volume, cardiac output and cardiac index * 2x 24-hours urine sample for sodium, potassium and creatine excretion * 1x plasma sample antidiuretic hormone, aldosterone and renin Intraoperative * Fluid responsiveness after 250 ml fluid administration * Nexfin monitoring * Fluid balance and amount of fluids administered (ml.kg-1.h-1) Postoperative * 3 times a day Nexfin parameters: Stroke Volume, Cardiac Output and Cardiac index. The first measurement is in the morning before mobilization and after 2 minutes mobilization (out of bed; standing of sitting on a chair). * Daily body weight and ankle & abdominal girth * 2x 24-hour urine sample with sodium, potassium and creatine excretion * First 5 days at the ward: daily measurement of electrolytes sodium, potassium, bicarbonate and chloride. * Daily measurements of plasma concentrations aldosterone, renin and antidiuretic hormone will be done before mobilization and after 20 minutes mobilization.

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Secondary

Measure	Time frame
nvt	—

Countries

Netherlands

Outcome results